ID you entered:  ENSP00000168977

Ensembl protein: ENSP00000168977   

          Protein sequence 
Name: NMRK2
Description: nicotinamide riboside kinase 2 [Source:HGNC Symbol;Acc:HGNC:17871]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :    NA
          Interaction partner with cancer related differentially expressed proteins :    NA

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs70883M173I1Melanoma21499247   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs146474422P76LCluster,Frequency,1000Genome
    2rs140113877R117QFrequency
    3rs144659918V122I1000Genome
    4rs199941317V149L1000Genome
    5rs150918954G164SFrequency
    6rs16992131E178KCluster,Frequency,1000Genome
    7rs138906846R181HCluster,Frequency
    8rs141476437S190*Cluster
    9rs181454061R194C1000Genome
    10rs146981587P202LCluster,Frequency,1000Genome
    11rs148078582R213LFrequency
    12rs150621748C215FCluster
    13rs35701787A223TCluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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