ID you entered:  ENSP00000170168

Ensembl protein: ENSP00000170168   

          Protein sequence 
Name: REXO1
Description: REX1, RNA exonuclease 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:24616]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.419042, hypergeometric test )
                 3 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs22262R263P-2Skin Cancer21984974   COSMIC
    2cs96977G977C-3Breast Cancer21930502  21930507   BIOMART
    3cs23636W998L-2Skin Cancer21984974   COSMIC
    4cs67291T1056I-1Head and Neck Cancer21984974   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs12984809S39PCluster,1000Genome
    2rs140861292A51S1000Genome
    3rs148700514A68V1000Genome
    4rs144017748P125S1000Genome
    5rs150151393V202ICluster
    6rs77108843R214CCluster,Frequency,1000Genome
    7rs145545644S226CFrequency
    8rs150047295T295MFrequency
    9rs147544709P313TCluster,Frequency,1000Genome
    10rs140993231P321LFrequency
    11rs188172131A386V1000Genome
    12rs10415018V408ACluster,Frequency,1000Genome
    13rs149519499R424WFrequency
    14rs12984503R429WCluster,Frequency
    15rs200225027R453WCluster,1000Genome
    16rs200648679A504TCluster
    17rs78977406A531T1000Genome
    18rs75443592E642KCluster
    19rs149465929E642-Cluster,1000Genome
    20rs12986305L649RHapMap
    21rs200306384S650LCluster
    22rs193012234K660N1000Genome
    23rs148840948G670DFrequency
    24rs186176871A681T1000Genome
    25rs200145449R697QCluster
    26rs183131082A716P1000Genome
    27rs79728211R731SCluster
    28rs190178425A742S1000Genome
    29rs141030694A753VFrequency
    30rs4807145S759PHapMap,1000Genome,Cluster,Frequency
    31rs139245703S776LFrequency
    32rs150815909I787VCluster
    33rs34831403I804VCluster,Frequency
    34rs61741977A850VCluster,Frequency,1000Genome
    35rs78904081S856TCluster
    36rs137920406A878TCluster,Frequency
    37rs2396359S886GHapMap,1000Genome,Cluster,Frequency
    38rs181549336V890A1000Genome
    39rs146851399A903TCluster,Frequency,1000Genome
    40rs202083742R911HCluster
    41rs142515155R916QFrequency
    42rs74401133A923VCluster,Frequency,1000Genome
    43rs145711847R1003QFrequency
    44rs77403452R1005WFrequency,1000Genome
    45rs7250083K1030MCluster
    46rs183172046G1054R1000Genome
    47rs142692445Y1072CCluster
    48rs182180858R1123C1000Genome
    49rs146587078M1132IFrequency
    50rs79814521R1186SCluster,1000Genome
    51rs150797218G1203SCluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



    [ continue search ]



    Dr. Jing Li's Group

    ©2015 Menghuan Zhang, Jing Li