ID you entered:  ENSP00000215582

Ensembl protein: ENSP00000215582   

          Protein sequence 
Name: MISP
Description: mitotic spindle positioning [Source:HGNC Symbol;Acc:HGNC:27000]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :    NA
          Interaction partner with cancer related differentially expressed proteins :    NA

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs32955R565W-3Head and Neck Cancer21798897   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs35093527Y31HCluster,Frequency,1000Genome
    2rs145024685Y68*1000Genome
    3rs141160817S84LFrequency
    4rs45477999A99TCluster,Frequency,1000Genome
    5rs45591331G116RCluster
    6rs151208927R125HCluster,Frequency,1000Genome
    7rs3746173S156GHapMap,1000Genome,Cluster,Frequency
    8rs145204788T172I1000Genome
    9rs78455638R188TCluster,Frequency,1000Genome
    10rs144643054F200LFrequency
    11rs189638901T219I1000Genome
    12rs147994311A230SCluster,Frequency,1000Genome
    13rs3746175K232RCluster,Frequency,1000Genome
    14rs74634086F234LCluster,Frequency,1000Genome
    15rs35384259S269NCluster,Frequency,1000Genome
    16rs138298423R311K1000Genome
    17rs34104245R314QCluster,Frequency,1000Genome
    18rs146641703R341QFrequency
    19rs141324306R342QFrequency
    20rs201182924S382*Cluster
    21rs201182924S382LCluster
    22rs151311263R390WCluster,1000Genome
    23rs140196930R390QFrequency
    24rs144396442A392V1000Genome
    25rs150331658S394TFrequency
    26rs137890735P410SFrequency
    27rs199803304A453VCluster
    28rs200675895A458VCluster,Frequency
    29rs190920819K476E1000Genome
    30rs143026376R510WCluster,1000Genome
    31rs116993988G527D1000Genome
    32rs142890248R556HCluster,Frequency,1000Genome
    33rs139858549R556C1000Genome
    34rs141415846R565QCluster,Frequency
    35rs184245064T577M1000Genome
    36rs185794418A617G1000Genome
    37rs8107847E653GCluster,Frequency,1000Genome
    38rs184988190R656Q1000Genome
    39rs145524738T658NCluster,Frequency,1000Genome
    40rs143887834R667HFrequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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