CanProVar 2.0:Human Cancer Proteome Variation Database

ID you entered: ENSP00000233997

Ensembl protein: ENSP00000233997

Protein sequence

Name: AZU1

Description: azurocidin 1 [Source:HGNC Symbol;Acc:HGNC:913]

Location:

chr19 p13.3

Gene Ontology:

Biological process

Molecular function

Cellular localization

Interactions:

Interaction partner with cancer_related variations : ( pvalue=0.165392, hypergeometric test )

Interaction partner with cancer related differentially expressed proteins : NA

Cancer-related variations in CanProVar:

NO.	csID	variation	change conservation⁺	Domain	cancer name	PubMed	data source⁺⁺	validated dbSNP*	interface
1	cs50231	R123C	-3	PF00089	Pancreatic Cancer		COSMIC

⁺Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
⁺⁺Data sources: HPI, COSMIC, OMIM, TCGA, BIOMART, Greenman2007, Sjoblom2006, Ding2008
*Cross-reference databases: dbSNP
Interface information was collected from Wang 2012

Non-cancer specific variations derived from database dbSNP:

NO.	dbSNP_ID	variation	validated
1	rs139128406	A19P	Frequency
2	rs148652041	R89Q	Frequency
3	rs142169722	D108Y	Frequency
4	rs140987452	T132M	Frequency
5	rs28664760	A141T	Cluster,Frequency,1000Genome
6	rs147872987	T142M	Cluster,Frequency,1000Genome
7	rs28626600	R158H	Cluster,Frequency,1000Genome
8	rs61732997	G161E	Cluster,Frequency
9	rs149180756	R162H	Frequency
10	rs61732996	R165H	Cluster,Frequency,1000Genome
11	rs141614223	N171K	Frequency
12	rs138374662	R193H	1000Genome
13	rs139615484	S218A	Frequency
14	rs149335820	L219M	Frequency
15	rs144687782	F235C	Frequency
16	rs147909830	G249R	Frequency

Cancer-related differential expression proteins derived from database dbDEPC:

No entry in dbDEPC was found

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