ID you entered:  ENSP00000234389

Ensembl protein: ENSP00000234389   

          Protein sequence 
Name: GRIN3B
Description: glutamate receptor, ionotropic, N-methyl-D-aspartate 3B [Source:HGNC Symbol;Acc:HGNC:16768]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.524242, hypergeometric test )
                 2 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs76257A583V0PF00060  PF00497  Head and Neck Cancer21798893   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs144440136A77T1000Genome
    2rs139242998A94E1000Genome
    3rs12986002H117YCluster,1000Genome
    4rs113181909P154SCluster,Frequency,1000Genome
    5rs2240154T157MCluster,Frequency,1000Genome
    6rs138359117A164V1000Genome
    7rs35592366D173ECluster,Frequency,1000Genome
    8rs149087926R197Q1000Genome
    9rs186778870R216W1000Genome
    10rs55646937R246HFrequency,1000Genome
    11rs143106549R247W1000Genome
    12rs61744452A319TCluster,Frequency,1000Genome
    13rs144334537R350H1000Genome
    14rs75047944G358DFrequency,1000Genome
    15rs373298742A380TCluster
    16rs12978900L396SCluster,Frequency,1000Genome
    17rs4807399R404WHapMap,1000Genome,Cluster,Frequency
    18rs2240157W414RCluster,Frequency,1000Genome,HapMap
    19rs201293199R418HCluster
    20rs199836408T421MCluster
    21rs61750461A458TCluster,Frequency,1000Genome
    22rs201453184E489ACluster
    23rs201453184E489GCluster
    24rs188035828I555S1000Genome
    25rs112116006W575*Cluster,1000Genome
    26rs2240158T577MHapMap,1000Genome,Cluster,Frequency
    27rs139187576R598CFrequency
    28rs139930791R606HFrequency
    29rs145253713R610CFrequency
    30rs60621387T612ACluster,Frequency,1000Genome
    31rs79866475V613ICluster
    32rs151255899R630CCluster,Frequency,1000Genome
    33rs147694026R643H1000Genome
    34rs78844421R643CCluster,Frequency,1000Genome
    35rs200400100M646VCluster
    36rs138448790S678LCluster
    37rs201299606S701I1000Genome
    38rs150675081I706V1000Genome
    39rs144432988P736AFrequency
    40rs148406831P737HFrequency
    41rs142637512M744TCluster,Frequency
    42rs146031397S747LFrequency
    43rs200432745G772SCluster
    44rs202092512R793CCluster
    45rs139755201G798SCluster,Frequency,1000Genome
    46rs77030329R816QCluster,Frequency,1000Genome
    47rs78914045A832ECluster,Frequency,1000Genome
    48rs2285906A845TCluster,Frequency,1000Genome
    49rs201161474G851RCluster
    50rs61744375E852KCluster,Frequency,1000Genome
    51rs181691646L883F1000Genome
    52rs74549450Q907RCluster,Frequency,1000Genome
    53rs10417824Y966NCluster,Frequency,1000Genome
    54rs145392111E982K1000Genome
    55rs10401245Q1006ECluster,Frequency,1000Genome
    56rs191196970R1020W1000Genome
    57rs10401454P1039RCluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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