ID you entered:  ENSP00000245817

Ensembl protein: ENSP00000245817   

          Protein sequence 
Name: TNFSF9
Description: tumor necrosis factor (ligand) superfamily, member 9 [Source:HGNC Symbol;Acc:HGNC:11939]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.274799, hypergeometric test )
                 4 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs73036M1I1Skin Cancer21984974   COSMIC
    2cs26939L124V1PF00229  Ovarian Cancer21720365   COSMICTNFRSF9

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs2234174A42TFrequency,1000Genome
    2rs2234175D80YCluster,Frequency,1000Genome
    3rs116463697I103VFrequency
    4rs115613976I103NFrequency
    5rs114086726I103MFrequency
    6rs61750000G139ACluster,Frequency,1000Genome
    7rs112025865R150QCluster,Frequency
    8rs77313944R150WCluster,1000Genome
    9rs34989544A177TCluster,Frequency,1000Genome
    10rs201036031A225TCluster
    11rs2234180G247RCluster,Frequency,1000Genome
    12rs184642529P251L1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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