ID you entered:  ENSP00000262966

Ensembl protein: ENSP00000262966   

          Protein sequence 
Name: MPND
Description: MPN domain containing [Source:HGNC Symbol;Acc:HGNC:25934]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.399627, hypergeometric test )
                 1 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs19836F314C-2PF01398  Ovarian Cancer21720365   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs192526108P108L1000Genome
    2rs144604946C143S1000Genome
    3rs117613418R235WFrequency,1000Genome
    4rs199844303N251S1000Genome
    5rs61730129A365TFrequency
    6rs34522164P423LCluster,1000Genome
    7rs79831308V426MCluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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