ID you entered:  ENSP00000264819

Ensembl protein: ENSP00000264819   

          Protein sequence 
Name: MIER2
Description: mesoderm induction early response 1, family member 2 [Source:HGNC Symbol;Acc:HGNC:29210]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.524242, hypergeometric test )
                 2 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs34141T526M-1Head and Neck Cancer21798893   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs147210482E19DFrequency
    2rs138561665S55TFrequency
    3rs7507468D68NCluster,Frequency
    4rs10421231D104NCluster
    5rs146065929R105WCluster,1000Genome
    6rs150312475Q140RCluster,Frequency,1000Genome
    7rs149957445S142FFrequency
    8rs112041836D145YCluster
    9rs112041836D145NCluster
    10rs112041836D145HCluster
    11rs201881025P148LCluster,Frequency
    12rs187460465R166H1000Genome
    13rs149432677P189SCluster,Frequency,1000Genome
    14rs199568910A254TCluster
    15rs148482834R289WFrequency
    16rs200376177P366LCluster
    17rs201519441R386HCluster
    18rs201519441R388HCluster
    19rs148132163T407MCluster,1000Genome
    20rs34129568P464SCluster,Frequency,1000Genome
    21rs35042658S485GCluster,Frequency,1000Genome
    22rs139223158H524QCluster


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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