ID you entered:  ENSP00000269740

Ensembl protein: ENSP00000269740   

          Protein sequence 
Name: SLC39A3
Description: solute carrier family 39 (zinc transporter), member 3 [Source:HGNC Symbol;Acc:HGNC:17128]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.724056, hypergeometric test )
                 1 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs30351E102K1PF02535  Head and Neck Cancer21984974   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs35127617R39HFrequency
    2rs11539244F100LCluster
    3rs199647177S125LCluster
    4rs145122585M138TCluster,Frequency,1000Genome
    5rs142446610R142QCluster
    6rs199646708A145TCluster
    7rs79259763V168MFrequency,1000Genome
    8rs140376410R169HCluster,Frequency,1000Genome
    9rs146790621G194R1000Genome
    10rs143540643V202MCluster,Frequency,1000Genome
    11rs35594294P257LFrequency
    12rs7252210V260MCluster,Frequency
    13rs200442678V305ICluster


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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