ID you entered:  ENSP00000296955

Ensembl protein: ENSP00000296955   

          Protein sequence 
Name: DCBLD1
Description: discoidin, CUB and LCCL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21479]
Location:
            chr6 q22.1
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.524242, hypergeometric test )
                 2 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs58794G140R-2PF00431  Breast Cancer21930502  21930507   BIOMART
    2cs57176T157K-1PF03815  Head and Neck Cancer21798893   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs117193276T71ACluster,Frequency,1000Genome
    2rs142641047V130ICluster,1000Genome
    3rs147487282P153SFrequency
    4rs184790040R161*1000Genome
    5rs139193542R222HFrequency
    6rs192563915R222C1000Genome
    7rs140824778G265RFrequency
    8rs144641172G302DCluster
    9rs77431098S305RCluster
    10rs201543589E315GCluster
    11rs74499389K356RCluster,Frequency,1000Genome
    12rs202127456V379LCluster
    13rs138996885I387VFrequency
    14rs182227121V388M1000Genome
    15rs138390701R424HCluster,1000Genome
    16rs13204101T440PHapMap
    17rs146613111S447W1000Genome
    18rs76270522E449KCluster
    19rs58391332K485QCluster
    20rs116943808M526LFrequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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