ID you entered:  ENSP00000300960

Ensembl protein: ENSP00000300960   

          Protein sequence 
Name: IZUMO4
Description: IZUMO family member 4 [Source:HGNC Symbol;Acc:26950]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :    NA
          Interaction partner with cancer related differentially expressed proteins :    NA

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs92082P197S-1Brain Cancer21930502  21930507   BIOMART
    2cs98599Q213K1Skin Cancer21984974   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs17851210A2TCluster
    2rs35585208F38LCluster,Frequency
    3rs147322963R131CFrequency
    4rs45506200Y137FCluster,Frequency,1000Genome
    5rs146424829S148LCluster,Frequency,1000Genome
    6rs139812380S160LFrequency
    7rs148904519G169DFrequency
    8rs143536329W177GFrequency
    9rs150988004T182MFrequency
    10rs140848704P197SCluster,Frequency,1000Genome
    11rs147056920C210RFrequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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