ID you entered:  ENSP00000302603

Ensembl protein: ENSP00000302603   

          Protein sequence 
Name: ZNF556
Description: zinc finger protein 556 [Source:HGNC Symbol;Acc:HGNC:25669]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.724056, hypergeometric test )
                 1 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs24627S66F-2Skin Cancer21984974   COSMIC
    2cs88446S329F-2PF00096  Melanoma21499247   COSMIC
    3cs87842A334T0PF00096  Pancreatic Cancer21930502  21930507   BIOMARTrs202052777

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs111290787T14M1000Genome
    2rs184566216E17A1000Genome
    3rs201408694Y29H1000Genome
    4rs142515332K70Q1000Genome
    5rs150895203R76G1000Genome
    6rs7251252E90DHapMap
    7rs139421960R102T1000Genome
    8rs143075091R122CCluster,Frequency,1000Genome
    9rs10421121R137CCluster,Frequency,1000Genome
    10rs138176298R146WCluster,Frequency,1000Genome
    11rs35499960R146LCluster,Frequency,1000Genome
    12rs34849844T157ICluster,Frequency,1000Genome
    13rs191337289I163M1000Genome
    14rs138582373T192MCluster,Frequency,1000Genome
    15rs61033781R214HCluster,Frequency,1000Genome
    16rs73519561H221RCluster,Frequency,1000Genome
    17rs142805889K229E1000Genome
    18rs148749321C236YFrequency
    19rs193201262S245F1000Genome
    20rs144505131G255RCluster,Frequency,1000Genome
    21rs139842259R275*Cluster
    22rs137990401P286LCluster,Frequency,1000Genome
    23rs184604557Q291R1000Genome
    24rs148855297R304*Frequency
    25rs199674434A323PCluster,1000Genome
    26rs202052777A334TCluster
    27rs141999811V348MFrequency
    28rs149449762S352PCluster,Frequency,1000Genome
    29rs35296337A353TCluster,Frequency,1000Genome
    30rs79688558A353VCluster,Frequency,1000Genome
    31rs139830711T374MCluster,Frequency,1000Genome
    32rs181113809S425N1000Genome
    33rs35494032E428KCluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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