ID you entered:  ENSP00000303696

Ensembl protein: ENSP00000303696   

          Protein sequence 
Name: ZNF57
Description: zinc finger protein 57 [Source:HGNC Symbol;Acc:HGNC:13125]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :    NA
          Interaction partner with cancer related differentially expressed proteins :    NA

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs41914D31E2PF01352  Skin Cancer21984974   COSMIC
    2cs55231D59H-1Head and Neck Cancer21798897   COSMIC
    3cs56332H122L-3Skin Cancer21984974   COSMIC
    4cs12707C341W-2Pancreatic Cancer21930502  21930507   BIOMART
    5cs40939H410Q0Ovarian Cancer18772890  21720365   TCGA, COSMIC
    6cs65445*556C-4Ovarian Cancer21720365   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs146287403D22Y1000Genome
    2rs148032465E35KCluster,Frequency,1000Genome
    3rs141912164R38WCluster
    4rs201085236S42P1000Genome
    5rs145789879V43IFrequency
    6rs139501492N52SCluster,1000Genome
    7rs143620899S56YFrequency
    8rs117724451S56ACluster,Frequency,1000Genome
    9rs151095249H103RCluster,Frequency,1000Genome
    10rs187461635A135P1000Genome
    11rs61743150T150MCluster,Frequency,1000Genome
    12rs61742111G187RCluster,Frequency,1000Genome
    13rs117830102P208SCluster,1000Genome
    14rs117830102P208TCluster,1000Genome
    15rs183418172H214R1000Genome
    16rs189035490V215I1000Genome
    17rs201768786T217ICluster
    18rs2288958T223NHapMap,1000Genome,Cluster,Frequency
    19rs145058495C229G1000Genome
    20rs2288957R230WCluster,Frequency,1000Genome
    21rs62125399R230QCluster
    22rs200613053S238GCluster
    23rs200527158Y280*1000Genome
    24rs149956507P292LFrequency
    25rs149956507P292HCluster,Frequency
    26rs61754927R297KCluster,Frequency,1000Genome
    27rs150372606T303MCluster,1000Genome
    28rs138288250Y308CCluster,Frequency,1000Genome
    29rs141285162R324QFrequency
    30rs184508498G332R1000Genome
    31rs55682587T357MCluster,Frequency,1000Genome
    32rs149542472E365DCluster,Frequency,1000Genome
    33rs143964698T387MCluster,Frequency
    34rs140956395A400PFrequency
    35rs149690257R408QFrequency
    36rs144519491G409DCluster
    37rs74837809Y420*Cluster,Frequency,1000Genome
    38rs142727006T443MCluster,Frequency,1000Genome
    39rs148920572M497ICluster,Frequency,1000Genome
    40rs143668692G510RCluster,Frequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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