ID you entered:  ENSP00000319053

Ensembl protein: ENSP00000319053   

          Protein sequence 
Name: ZNF77
Description: zinc finger protein 77 [Source:HGNC Symbol;Acc:HGNC:13150]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :    NA
          Interaction partner with cancer related differentially expressed proteins :    NA

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs94025R508H0Ovarian Cancer21720365   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs12610412C3SHapMap,1000Genome,Cluster,Frequency
    2rs12609268I5VHapMap,1000Genome,Cluster,Frequency
    3rs76204804V11GCluster
    4rs140838873P15SFrequency
    5rs34603238L20WCluster,Frequency
    6rs140476712Q25*1000Genome
    7rs186272618S52G1000Genome
    8rs144419578Q57EFrequency
    9rs114126245G64RCluster,Frequency,1000Genome
    10rs145532951N67S1000Genome
    11rs189959170R88G1000Genome
    12rs200864167T92ACluster
    13rs35699176Q100*Cluster,Frequency,1000Genome
    14rs34184381H132QCluster,Frequency,1000Genome
    15rs76396690C144FCluster,Frequency,1000Genome
    16rs141883841C167YCluster,Frequency,1000Genome
    17rs34727043S175ACluster,Frequency,1000Genome
    18rs34705382P179SCluster,Frequency,1000Genome
    19rs182952893T183M1000Genome
    20rs73527668V186ICluster,Frequency,1000Genome
    21rs10423550Y202*HapMap,1000Genome,Cluster,Frequency
    22rs201277177V203MCluster
    23rs35941441P224HCluster,Frequency,1000Genome
    24rs199713360G229VCluster
    25rs139212127R257WFrequency
    26rs140137786R284*1000Genome
    27rs141673139P295LCluster
    28rs151130031T317MCluster,Frequency,1000Genome
    29rs200559103H328RCluster
    30rs146879198R340*Frequency
    31rs199562140T345MCluster
    32rs61740279R368*Cluster,Frequency
    33rs182743134V427M1000Genome
    34rs35411355G460RCluster,Frequency,1000Genome
    35rs142625963P463RCluster,1000Genome
    36rs142625963P463LCluster,1000Genome
    37rs139829692A476DFrequency
    38rs190727318Q480K1000Genome
    39rs34789013Y492*Cluster,Frequency,1000Genome
    40rs201394063T513MCluster


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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