ID you entered:  ENSP00000327368

Ensembl protein: ENSP00000327368   

          Protein sequence 
Name: COL10A1
Description: collagen, type X, alpha 1 [Source:HGNC Symbol;Acc:HGNC:2185]
Location:
            chr6 q22.1
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.434049, hypergeometric test )
                 2 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs11460G18V-3Head and Neck Cancer21798893   COSMIC
    2cs29348G115*-4PF01391  Central Nervous System Neoplasms21163964   COSMIC
    3cs42171G168E-2Skin Cancer21984974   COSMIC
    4cs73435G338R-2Skin Cancer21984974   COSMIC
    5cs88860Q635L-2PF00386  Skin Cancer21984974   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs34539681L8WCluster,Frequency,1000Genome
    2rs147612968L15VFrequency
    3rs111033551G18ECluster
    4rs111033550G18RCluster
    5rs199808053R24*Cluster
    6rs1064583M27TCluster,Frequency,1000Genome
    7rs142411445S50RCluster,Frequency,1000Genome
    8rs145214720G86RFrequency
    9rs2243370G98RCluster,Frequency
    10rs142463796D128N1000Genome
    11rs151327195R138QFrequency
    12rs148785195R198HCluster,Frequency,1000Genome
    13rs146114911G209SCluster,1000Genome
    14rs202057046G229ACluster
    15rs202057046G229ECluster
    16rs188598435P249R1000Genome
    17rs144479322R258QFrequency
    18rs183121424G305V1000Genome
    19rs78492100G318RCluster
    20rs145378345G383R1000Genome
    21rs201088230P406RCluster
    22rs143728723G415ECluster
    23rs146784716G455VCluster
    24rs143928308F462LCluster
    25rs2228547G545RCluster,Frequency,1000Genome
    26rs142108410M549IFrequency
    27rs191382529P568L1000Genome
    28rs111033546C591RCluster
    29rs111033553G595ECluster
    30rs111033554Y597CCluster
    31rs111033544Y598DCluster
    32rs111033555S600PCluster
    33rs111033556W611*Cluster
    34rs111033545L614PCluster
    35rs111033543Y628*Cluster
    36rs111033548Y632*Cluster
    37rs111033547W651*Cluster
    38rs111033549W651RCluster
    39rs111033552S671PCluster


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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