ID you entered:  ENSP00000329697

Ensembl protein: ENSP00000329697   

          Protein sequence 
Name: PPAP2C
Description: phosphatidic acid phosphatase type 2C [Source:HGNC Symbol;Acc:HGNC:9230]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.379258, hypergeometric test )
                 4 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs45171S162L-2PF01569  Breast Cancer21930502  21930507   BIOMART
    2cs95550A201T0PF01569  Central Nervous System Neoplasms18772396   COSMIC
    3cs18192*310S-4Ovarian Cancer21720365   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs183614327P26R1000Genome
    2rs150705131R55QFrequency
    3rs144086136G60RFrequency
    4rs138517226D62VCluster
    5rs148329482V87ICluster,1000Genome
    6rs181354682S91L1000Genome
    7rs61745392R106CCluster,Frequency,1000Genome
    8rs140076000R158QCluster
    9rs185214238A176T1000Genome
    10rs201440917S187LCluster
    11rs199617258W210*Cluster
    12rs201408221R214WCluster
    13rs61738956C262RCluster,Frequency
    14rs34708574R284WCluster,Frequency,1000Genome
    15rs34392164P305SCluster,Frequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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