ID you entered:  ENSP00000330264

Ensembl protein: ENSP00000330264   

          Protein sequence 
Name: TMPRSS9
Description: transmembrane protease, serine 9 [Source:HGNC Symbol;Acc:HGNC:30079]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :    NA
          Interaction partner with cancer related differentially expressed proteins :    NA

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs16579L144V1Ovarian Cancer18772890  21720365   TCGA, COSMIC
    2cs79254P211L-3PF00089  Central Nervous System Neoplasms21163964   COSMIC
    3cs81047S397F-2PF00089  Skin Cancer21984974   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs8100709T4ACluster,Frequency,1000Genome
    2rs185668001V11L1000Genome
    3rs142722059K16NFrequency
    4rs891174S30TCluster,Frequency,1000Genome
    5rs17685098R73WCluster,Frequency,1000Genome
    6rs142862960R74WFrequency
    7rs146586207T82MCluster
    8rs140023303T86IFrequency
    9rs140728595L98FFrequency
    10rs145333061R112QFrequency
    11rs141214525I131VCluster,Frequency,1000Genome
    12rs141796619R153CCluster
    13rs201603131C166*Cluster
    14rs150598683A187VFrequency
    15rs200531836G201SCluster
    16rs117767265A218VCluster,Frequency,1000Genome
    17rs146089494R221GFrequency
    18rs143556680D250NCluster,Frequency,1000Genome
    19rs144060578T252MCluster,Frequency,1000Genome
    20rs184338854S266L1000Genome
    21rs142962468R272WFrequency
    22rs141038366V279IFrequency
    23rs62120714R306QCluster,Frequency,1000Genome
    24rs201051608G330R1000Genome
    25rs148284151S360TFrequency
    26rs141237109G363SFrequency
    27rs138847400R369GFrequency
    28rs147023760A415TCluster,Frequency,1000Genome
    29rs145109209R417HCluster,Frequency
    30rs150090870R428CCluster,Frequency,1000Genome
    31rs10153474A456TCluster,Frequency,1000Genome
    32rs145686165A497GFrequency
    33rs201661905C529*Cluster
    34rs145601770A543TCluster,Frequency,1000Genome
    35rs147705810R577QCluster,Frequency,1000Genome
    36rs116272666I617TCluster,Frequency,1000Genome
    37rs147534568V622MFrequency
    38rs45546534Q635RCluster,Frequency,1000Genome
    39rs143993870K656ECluster,Frequency
    40rs60568869S659TCluster,Frequency,1000Genome
    41rs144100598T722MCluster,Frequency,1000Genome
    42rs139183825S746LCluster,Frequency
    43rs138523679T758MFrequency
    44rs149635897T763RFrequency
    45rs735911S793NCluster,Frequency,1000Genome
    46rs34615361G798RCluster,Frequency,1000Genome
    47rs191349620R835H1000Genome
    48rs184330957I934V1000Genome
    49rs7247162E938KCluster,1000Genome
    50rs141671587R1021QCluster,1000Genome
    51rs147027818G1033SFrequency
    52rs140960972H1038PFrequency
    53rs7252121T1044ICluster,Frequency,1000Genome
    54rs147580035W1052*1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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