ID you entered:  ENSP00000332151

Ensembl protein: ENSP00000332151   

          Protein sequence 
Name: DSE
Description: dermatan sulfate epimerase [Source:HGNC Symbol;Acc:HGNC:21144]
Location:
            chr6 q22.1
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.434049, hypergeometric test )
                 2 
          Interaction partner with cancer related differentially expressed proteins :  (  pvalue=0.106365, hypergeometric test )
                 2 
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs20420H603Y2Skin Cancer21984974   COSMIC
    2cs48693G881R-2Head and Neck Cancer21798893   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs142885560F12YFrequency
    2rs76186865C18FCluster,Frequency,1000Genome
    3rs41352449T25ICluster,Frequency
    4rs10485183T25ICluster,Frequency,1000Genome
    5rs140765634M32TFrequency
    6rs35548455P34LCluster,Frequency,1000Genome
    7rs147683614R70HCluster,Frequency,1000Genome
    8rs112379267T215MCluster,Frequency
    9rs34994230I282VCluster,Frequency,1000Genome
    10rs41313440V381ACluster,Frequency,1000Genome
    11rs150311697A408TCluster,Frequency,1000Genome
    12rs181711422A461T1000Genome
    13rs187363456P563S1000Genome
    14rs61741781R654QCluster,Frequency
    15rs148121424K691RCluster,1000Genome
    16rs140975523S707CCluster,Frequency,1000Genome
    17rs192004599A768G1000Genome
    18rs150197356Q802L1000Genome
    19rs182628432D853E1000Genome
    20rs138438397G873-1000Genome
    21rs113277624R879WCluster,Frequency
    22rs35363262R884QCluster,Frequency,1000Genome
    23rs149649831L896RFrequency
    24rs143226402T921AFrequency
    25rs146336077W948RFrequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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