ID you entered:  ENSP00000335333

Ensembl protein: ENSP00000335333   

          Protein sequence 
Name: PIP5K1C
Description: phosphatidylinositol-4-phosphate 5-kinase, type I, gamma [Source:HGNC Symbol;Acc:HGNC:8996]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.379258, hypergeometric test )
                 4 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs62396R304W-3PF01504  Gastric Cancer21097718   COSMIC
    2cs74690S534F-2Melanoma21499247   COSMIC
    3cs70536L652F0Gastric Cancer21097718   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs2301850G88SCluster,Frequency
    2rs146890276R331CCluster,Frequency,1000Genome
    3rs115148108R333Q1000Genome
    4rs145192608A338TFrequency
    5rs115799086R367H1000Genome
    6rs145110523R386HCluster,Frequency,1000Genome
    7rs141550581G460SCluster,Frequency,1000Genome
    8rs199563464E483KCluster
    9rs79423827S539PCluster
    10rs139195886R550GCluster,Frequency
    11rs115654072A568VCluster,Frequency,1000Genome
    12rs35014191A656TCluster,Frequency,1000Genome
    13rs34633286P659SCluster,Frequency
    14rs202073714D663NCluster
    15rs200509774E665KCluster


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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