ID you entered:  ENSP00000354733

Ensembl protein: ENSP00000354733   

          Protein sequence 
Name: SBNO2
Description: strawberry notch homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:29158]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.724056, hypergeometric test )
                 1 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs57844E456K1Head and Neck Cancer21798893   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs199901218T73ACluster
    2rs192343149E381Q1000Genome
    3rs201453059A392S1000Genome
    4rs187430722E450*1000Genome
    5rs183150602E450V1000Genome
    6rs201652801E500KCluster
    7rs186815421A599V1000Genome
    8rs200987793R724QCluster
    9rs11880694A1106VCluster,1000Genome,HapMap
    10rs201689400R1116LCluster
    11rs201689400R1116QCluster
    12rs200551019A1180D1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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