ID you entered:  ENSP00000357597

Ensembl protein: ENSP00000357597   

          Protein sequence 
Name: TSPYL1
Description: TSPY-like 1 [Source:HGNC Symbol;Acc:HGNC:12382]
Location:
            chr6 q22.1
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.379559, hypergeometric test )
                 3 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs50962E225*-4Ovarian Cancer21720365   COSMIC
    2cs49136Y303*-4PF00956  Ovarian Cancer21720365   COSMICTSPYL1

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs200419841G50ACluster,Frequency
    2rs3828743P62SCluster,Frequency,1000Genome
    3rs3749895A74PCluster,Frequency,1000Genome
    4rs149638466V86ICluster,Frequency,1000Genome
    5rs138299432A93VFrequency
    6rs61746508Q126HCluster,Frequency,1000Genome
    7rs138602300A131VCluster,Frequency,1000Genome
    8rs144647131V163ICluster
    9rs200977893G179V1000Genome
    10rs3749894A181TCluster,Frequency,1000Genome
    11rs147978697E201KFrequency
    12rs144676525I356TCluster,Frequency,1000Genome
    13rs140756663F366LFrequency
    14rs45490498T379SCluster,Frequency,1000Genome
    15rs45490498T379ACluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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