ID you entered:  ENSP00000378630

Ensembl protein: ENSP00000378630   

          Protein sequence 
Name: ZNF57
Description: zinc finger protein 57 [Source:HGNC Symbol;Acc:13125]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :    NA
          Interaction partner with cancer related differentially expressed proteins :    NA

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs46228C343W-2Pancreatic Cancer21930502  21930507   BIOMART

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs146287403D22Y1000Genome
    2rs148032465E35KCluster,Frequency,1000Genome
    3rs145789879V43IFrequency
    4rs139501492N52SCluster,1000Genome
    5rs117724451S56ACluster,Frequency,1000Genome
    6rs143620899S56YFrequency
    7rs151095249H105RCluster,Frequency,1000Genome
    8rs187461635A137P1000Genome
    9rs61743150T152MCluster,Frequency,1000Genome
    10rs61742111G189RCluster,Frequency,1000Genome
    11rs117830102P210SCluster,1000Genome
    12rs117830102P210TCluster,1000Genome
    13rs183418172H216R1000Genome
    14rs189035490V217I1000Genome
    15rs2288958T225NHapMap,1000Genome,Cluster,Frequency
    16rs145058495C231G1000Genome
    17rs2288957R232WCluster,Frequency,1000Genome
    18rs149956507P294LFrequency
    19rs61754927R299KCluster,Frequency,1000Genome
    20rs150372606T305MCluster,1000Genome
    21rs138288250Y310CCluster,Frequency,1000Genome
    22rs141285162R326QFrequency
    23rs184508498G334R1000Genome
    24rs55682587T359MCluster,Frequency,1000Genome
    25rs149542472E367DCluster,Frequency,1000Genome
    26rs140956395A402PFrequency
    27rs149690257R410QFrequency
    28rs74837809Y422*Cluster,Frequency,1000Genome
    29rs142727006T445MCluster,Frequency,1000Genome
    30rs148920572M499ICluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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