ID you entered:  ENSP00000420357

Ensembl protein: ENSP00000420357   

          Protein sequence 
Name: RWDD1
Description: RWD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20993]
Location:
            chr6 q22.1
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.110137, hypergeometric test )
                 2 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs36118Q108P-1PF05773  Breast Cancer21930502  21930507   BIOMART
    2cs95061W154*-4Breast Cancer21930502  21930507   BIOMART
    3cs91384E227K1Breast Cancer21930502  21930507   BIOMART

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs144557301D62G1000Genome
    2rs180736980Q117H1000Genome
    3rs144112809E130KFrequency
    4rs147351925D220EFrequency
    5rs11542526D225NHapMap
    6rs61739545D236AFrequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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