ID you entered:  ENSP00000440332

Ensembl protein: ENSP00000440332   

          Protein sequence 
Name: HS3ST5
Description: heparan sulfate (glucosamine) 3-O-sulfotransferase 5 [Source:HGNC Symbol;Acc:HGNC:19419]
Location:
            chr6 q22.1
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :    NA
          Interaction partner with cancer related differentially expressed proteins :    NA

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs33841*347S-4Ovarian Cancer21720365   COSMIC
    2cs60105*347C-4Ovarian Cancer21720365   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs144143119A29TFrequency
    2rs191330212I43T1000Genome
    3rs139315971L61PFrequency
    4rs148289240A93VCluster,Frequency,1000Genome
    5rs144094472P114SCluster,Frequency,1000Genome
    6rs138458938K225QCluster,Frequency
    7rs17793043I247NCluster,Frequency,1000Genome
    8rs150930343V253IFrequency
    9rs140386644V269LFrequency
    10rs149977661N344Y1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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