ID you entered:  ENSP00000252542

Ensembl protein: ENSP00000252542   

          Protein sequence 
Name: SAFB2
Description: scaffold attachment factor B2 [Source:HGNC Symbol;Acc:HGNC:21605]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.073512, hypergeometric test )
                 36 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs19220S132N1Ovarian Cancer21720365   COSMIC
    2cs26854T561I-1Head and Neck Cancer21798893   COSMIC
    3cs12970H915N1Skin Cancer21984974   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs75447127K65*Cluster
    2rs140521200L123MCluster
    3rs147855487G154CCluster
    4rs56111887G303SCluster
    5rs202189507E386G1000Genome
    6rs200501014D389G1000Genome
    7rs149456738R400WCluster
    8rs150768449V453ICluster,1000Genome
    9rs193920906S456LCluster
    10rs61748936T457ACluster,Frequency,1000Genome
    11rs147906448E515DCluster,Frequency,1000Genome
    12rs146495537K535EFrequency
    13rs141670762A756SFrequency
    14rs150472516G815SFrequency
    15rs140108933G824C1000Genome
    16rs180719319A861T1000Genome
    17rs142474489R897CFrequency
    18rs28703771Q913RCluster


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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