ID you entered:  ENSP00000252587

Ensembl protein: ENSP00000252587   

          Protein sequence 
Name: CREB3L3
Description: cAMP responsive element binding protein 3-like 3 [Source:HGNC Symbol;Acc:18855]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.0546396, hypergeometric test )
                 9 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs18741T169P-1Breast Cancer21930502  21930507   BIOMART

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs149387566L17PFrequency
    2rs77002741G95RCluster,Frequency,1000Genome
    3rs145839480G102SFrequency
    4rs150887508H104PFrequency
    5rs77528283P108ACluster,1000Genome
    6rs77528283P108TCluster,1000Genome
    7rs149917178G111EFrequency
    8rs147422200S196L1000Genome
    9rs184235585A232V1000Genome
    10rs143545033P236LCluster,Frequency,1000Genome
    11rs145017010E281KFrequency
    12rs140601919P288LCluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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