ID you entered:  ENSP00000292123

Ensembl protein: ENSP00000292123   

          Protein sequence 
Name: SAFB
Description: scaffold attachment factor B [Source:HGNC Symbol;Acc:HGNC:10520]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.158048, hypergeometric test )
                 23 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs66978V144I3Ovarian Cancer21720365   COSMIC
    2cs1139V487M1Melanoma COSMIC
    3cs16216R585G-2Hepatocellular Carcinoma COSMIC
    4cs46455Q743K1Hepatocellular Carcinoma21930502  21930507   BIOMART
    5cs75022R913G-2Ovarian Cancer21720365   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs61760907L120VCluster
    2rs182749782D151N1000Genome
    3rs76200723I201TCluster,1000Genome
    4rs56111887G304SCluster
    5rs191587894S504L1000Genome
    6rs201328292K522TCluster
    7rs74848969D530ECluster
    8rs202238628D538H1000Genome
    9rs11542075D540HHapMap
    10rs183340183P544R1000Genome
    11rs188904085R551Q1000Genome
    12rs140739982R626CCluster,Frequency
    13rs75098084A653GCluster
    14rs201302062G755SCluster
    15rs181988846D829E1000Genome
    16rs143761159G895ECluster,Frequency
    17rs143761159G896EFrequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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