ID you entered:  ENSP00000301280

Ensembl protein: ENSP00000301280   

          Protein sequence 
Name: CHAF1A
Description: chromatin assembly factor 1, subunit A (p150) [Source:HGNC Symbol;Acc:HGNC:1910]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.0750618, hypergeometric test )
                 54 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs95655R515Q1Ovarian Cancer18772890  21720365   TCGA, COSMIC
    2cs75839S526F-2Melanoma21499247   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs193058821L102S1000Genome
    2rs148067278Q126RFrequency
    3rs141725942L130FFrequency
    4rs35651457D167VCluster,Frequency,1000Genome
    5rs200445124G192S1000Genome
    6rs143288325S224GCluster,Frequency,1000Genome
    7rs184354515L232P1000Genome
    8rs2230635M239VCluster,Frequency,1000Genome
    9rs148594897V241GCluster
    10rs112968308P250LCluster,Frequency
    11rs188543074D279H1000Genome
    12rs143513152E297K1000Genome
    13rs149123603F325IFrequency
    14rs201966580V326ICluster
    15rs150835577A486TFrequency
    16rs45499793A708TCluster,Frequency
    17rs199658685C761YCluster
    18rs115461571R763QCluster,Frequency,1000Genome
    19rs201972593T783ICluster
    20rs45597332R797QCluster,Frequency,1000Genome
    21rs8100525K850RCluster,Frequency,1000Genome
    22rs149907294S868LFrequency
    23rs147615871T943AFrequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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