ID you entered:  ENSP00000317912

Ensembl protein: ENSP00000317912   

          Protein sequence 
Name: STAP2
Description: signal transducing adaptor family member 2 [Source:HGNC Symbol;Acc:30430]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.120145, hypergeometric test )
                 10 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs75512E161A-1Central Nervous System Neoplasms18772396   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs7247504D93NCluster,Frequency,1000Genome,HapMap
    2rs143484969R146CFrequency
    3rs79657645Y169*Cluster,Frequency,1000Genome
    4rs79097338V187LCluster,Frequency,1000Genome
    5rs146537896C281RFrequency
    6rs144306660T282IFrequency
    7rs143576049S330AFrequency
    8rs138002546A346GFrequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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