ID you entered:  ENSP00000318075

Ensembl protein: ENSP00000318075   

          Protein sequence 
Name: PLEKHJ1
Description: pleckstrin homology domain containing, family J member 1 [Source:HGNC Symbol;Acc:HGNC:18211]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.307292, hypergeometric test )
                 6 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs56426*150L-4Head and Neck Cancer21798893   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs200839174S107NCluster
    2rs200038136E109KCluster
    3rs200034375E121KCluster
    4rs34499026R123QCluster,Frequency,1000Genome
    5rs146362675T126MFrequency
    6rs200815516I136M1000Genome
    7rs187259747E138K1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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