ID you entered:  ENSP00000320493

Ensembl protein: ENSP00000320493   

          Protein sequence 
Name: TRIP10
Description: thyroid hormone receptor interactor 10 [Source:HGNC Symbol;Acc:HGNC:12304]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.174169, hypergeometric test )
                 17 
          Interaction partner with cancer related differentially expressed proteins :  (  pvalue=0.0465225, hypergeometric test )
                 8 
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs53986D260N1Ovarian Cancer18772890  21720365   TCGA, COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs142559634L89PFrequency
    2rs140280835R97HCluster
    3rs140367724R122QCluster
    4rs34329946Q133ECluster,Frequency
    5rs144960247R179QCluster
    6rs137899128S180G1000Genome
    7rs192595827Y205C1000Genome
    8rs201404450F206CCluster
    9rs112745359S235*Cluster
    10rs112745359S235LCluster
    11rs112745359S235WCluster
    12rs188886975N292S1000Genome
    13rs201134453R354HCluster,1000Genome
    14rs140822183S386GFrequency
    15rs146733712L403FFrequency
    16rs200262718R432QCluster
    17rs28705365P436SCluster,Frequency,1000Genome
    18rs34808063A440TCluster,Frequency
    19rs144118150E459QFrequency
    20rs139253875E507KFrequency


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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