ID you entered:  ENSP00000323670

Ensembl protein: ENSP00000323670   

          Protein sequence 
Name: ZBTB7A
Description: zinc finger and BTB domain containing 7A [Source:HGNC Symbol;Acc:HGNC:18078]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.00785765, hypergeometric test )
                 15 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs97360E115*-4PF00651  Pancreatic Cancer COSMIC
    2cs35266Y466D-3Skin Cancer21984974   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs189465312A102T1000Genome
    2rs75584722I131VCluster
    3rs78855889L132QCluster
    4rs77059506A133VCluster
    5rs76930783A133PCluster
    6rs147200385A136PFrequency
    7rs200634461A175V1000Genome
    8rs3745985A177TCluster,1000Genome
    9rs192002499N269T1000Genome
    10rs80178467G560VCluster


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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