ID you entered:  ENSP00000327313

Ensembl protein: ENSP00000327313   

          Protein sequence 
Name: PTPRS
Description: protein tyrosine phosphatase, receptor type, S [Source:HGNC Symbol;Acc:HGNC:9681]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.14734, hypergeometric test )
                 19 
          Interaction partner with cancer related differentially expressed proteins :  (  pvalue=0.196994, hypergeometric test )
                 5 
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs64559T563M-1PF00041  Pancreatic Cancer21930502  21930507   BIOMART

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs61729776C27YCluster,Frequency,1000Genome
    2rs115231439K40R1000Genome
    3rs146675930T80MCluster,Frequency
    4rs114080870V113ACluster,Frequency,1000Genome
    5rs139336866N136SCluster
    6rs79960932S352TCluster
    7rs79388082S352FCluster
    8rs138765579A582TCluster
    9rs3202678F670LHapMap
    10rs201447856T685MCluster
    11rs115469963R763HCluster,1000Genome
    12rs115469963R767HCluster,1000Genome
    13rs114904537H794N1000Genome
    14rs202091186R814HCluster
    15rs114545401A980TCluster,1000Genome
    16rs147152459T1067MCluster
    17rs148739536R1165QFrequency
    18rs142364974R1165WCluster,Frequency
    19rs61729772G1231CFrequency
    20rs1064301N1262KHapMap


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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