ID you entered:  ENSP00000332208

Ensembl protein: ENSP00000332208   

          Protein sequence 
Name: RFX6
Description: regulatory factor X, 6 [Source:HGNC Symbol;Acc:HGNC:21478]
Location:
            chr6 q22.1
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.286061, hypergeometric test )
                 7 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs98477Q15L-2Ovarian Cancer18772890  21720365   TCGA, COSMIC
    2cs18370A17E-1Pancreatic Cancer COSMIC
    3cs88877Q483K1Melanoma21499247   COSMIC
    4cs54575S700N1Head and Neck Cancer21798893   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs9489056A17ECluster,Frequency,1000Genome
    2rs146773792S21YFrequency
    3rs201996097E75QCluster,1000Genome
    4rs145678004E130GFrequency
    5rs188277006R229H1000Genome
    6rs79514672Y268*Cluster
    7rs183355578Q296K1000Genome
    8rs139343836V329ICluster,1000Genome
    9rs146115506R578PCluster,Frequency,1000Genome
    10rs145210672M583VFrequency
    11rs150973410L610PFrequency
    12rs137956032D623E1000Genome
    13rs188704301R652*1000Genome
    14rs146081967T680KFrequency
    15rs149748658E683Q1000Genome
    16rs17857184T688AHapMap
    17rs144648002R726GCluster,Frequency,1000Genome
    18rs582803S743NCluster
    19rs181546283Y749H1000Genome
    20rs57924353G790ECluster,Frequency,1000Genome
    21rs142162854R813TFrequency
    22rs57748743R829PFrequency,1000Genome
    23rs145117989Q851HCluster,Frequency,1000Genome


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



    [ continue search ]



    Dr. Jing Li's Group

    ©2015 Menghuan Zhang, Jing Li