ID you entered:  ENSP00000341483

Ensembl protein: ENSP00000341483   

          Protein sequence 
Name: RANBP3
Description: RAN binding protein 3 [Source:HGNC Symbol;Acc:HGNC:9850]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.252935, hypergeometric test )
                 9 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs67273G141V-3Ovarian Cancer21720365   COSMIC
    2cs66633E234Q2Breast Cancer17932254   COSMIC
    3cs35776G422D-1PF00638  Ovarian Cancer21720365   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs202177264R169WCluster
    2rs192303973A209T1000Genome
    3rs188627819E246K1000Genome
    4rs201812693A255TCluster
    5rs182675323E279K1000Genome
    6rs115320782D281NFrequency,1000Genome
    7rs199604597D291ECluster
    8rs10417885A314VCluster,Frequency,1000Genome
    9rs187356108N345S1000Genome
    10rs188045006D466N1000Genome
    11rs183601024E535K1000Genome
    12rs35895100G561RCluster


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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