ID you entered:  ENSP00000410369

Ensembl protein: ENSP00000410369   

          Protein sequence 
Name: FZR1
Description: fizzy/cell division cycle 20 related 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:24824]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.13882, hypergeometric test )
                 30 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs2328V253A0PF00400  Lung Cancer COSMIC
    2cs45447Q350L-2PF00400  Head and Neck Cancer21798893   COSMIC
    3cs77795Q401*-4Renal Cancer21248752   COSMIC
    4cs44403R493Q1Head and Neck Cancer21798893   COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:

    • NO.dbSNP_IDvariationvalidated
    1rs139197779K69T1000Genome
    2rs144842420R169HCluster,Frequency
    3rs140377183M266TFrequency
    4rs202153731M292VCluster
    5rs11542322C395RHapMap


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



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