ID you entered:  ENSP00000480564

Ensembl protein: ENSP00000480564   

          Protein sequence 
Name: TCF3
Description: transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11633]
Location:
            chr19 p13.3
Gene Ontology:
           Biological process 
           Molecular function 
           Cellular localization 
Interactions:   
          Interaction partner with cancer_related variations :  (  pvalue=0.00384976, hypergeometric test )
                 45 
          Interaction partner with cancer related differentially expressed proteins :    NA
                         

  • Cancer-related variations in CanProVar:
    • NO.csIDvariationchange conservation+Domaincancer namePubMeddata source++validated dbSNP*interface
    1cs54470A8S1Intestines Cancer COSMIC
    2cs4817A8V0Intestines Cancer16959974   COSMIC
    3cs46518V10A0Renal Cancer COSMIC
    4cs74421V10L1Lung Cancer20668451   COSMIC
    5cs90809L20R-2Ovarian Cancer COSMIC
    6cs51969A41T0Liver Cancer COSMIC
    7cs22668R105Q1Thyroid Carcinoma COSMIC
    8cs39243A107T0Gastric Cancer COSMIC
    9cs39243A107T0Uterine Cancer COSMIC
    10cs58492L120P-3Liver Cancer COSMIC
    11cs69597S134N1Renal Cancer COSMIC
    12cs66980S157Y-2Intestines Cancer COSMIC
    13cs26012R159W-3Lung Cancer COSMIC
    14cs87843R160I-3Intestines Cancer COSMIC
    15cs91814T168M-1Central Nervous System Neoplasms COSMIC
    16cs91814T168M-1Intestines Cancer COSMIC
    17cs27098P201S-1Skin Cancer(Melanoma) COSMIC
    18cs87982D218E2Breast Cancer20668451   COSMIC
    19cs40937P255Q-1Lymphocytic Leukemia23415222   COSMIC
    20cs20490G298*-4Thyroid Carcinoma COSMIC
    21cs53935S359F-2Liver Cancer COSMIC
    22cs76254R371*-4Intestines Cancer COSMIC
    23cs11627S391T1Central Nervous System Neoplasms23917401   COSMIC
    24cs13502G431S0Lung Cancer20505728   COSMIC
    25cs76287G470C-3Lung Cancer COSMIC
    26cs23925S476C-1Lung Cancer COSMIC
    27cs42422G486W-2Thyroid Carcinoma COSMIC
    28cs47493T491M-1Skin Cancer21984974   COSMIC
    29cs12708K518E1Intestines Cancer COSMIC
    30cs20529A544V0Intestines Cancer COSMIC
    31cs95496E545K1Lung Cancer20668451   COSMIC
    32cs68041R557W-3Intestines Cancer COSMICTCF4, TAL1, MYF5, MYF6, T
    33cs21950R559W-3Intestines Cancer22895193   COSMICTCF4, TAL1, MYF5, MYF6, T
    34cs21950R559W-3Lymphocytic Leukemia23856246   COSMICTCF4, TAL1, MYF5, MYF6, T
    35cs33279R561W-3Breast Cancer COSMICTCF4, TAL1, MYF5, MYF6, T
    36cs34231R563C-3Gastric Cancer COSMICTCF4, TAL1, MYF5, MYF6, T
    37cs71166E567K1Gastric Cancer COSMICTCF4, TAL1, MYF5, MYF6, T
    38cs71166E567K1Uterine Cancer COSMICTCF4, TAL1, MYF5, MYF6, T
    39cs26851L572M2Uterine Cancer COSMICTCF4, TAL1, MYF5, MYF6, T
    40cs38216R574H0Gastric Cancer COSMICTCF4, TAL1, MYF5, MYF6, T
    41cs56923V598I3Lymphocytic Leukemia23856246   COSMICTCF4, TAL1, MYF5, MYF6, T
    42cs18764R607Q1Lymphocytic Leukemia COSMIC
    43cs53165R607*-4Uterine Cancer COSMIC
    44cs45987R609Q1Lymphocytic Leukemia COSMIC
    45cs93842R621*-4Uterine Cancer COSMIC
    46cs66723P633L-3Ovarian Cancer20668451   COSMIC
    47cs10874P640L-3Skin Cancer(Melanoma) COSMIC

    +Conservation of amino acid substitutions are defined here according to the BLOSUM62 matrix, conservative changes were those having a positive or neutral sign in the matrix, whereas non-conservative changes were those having a negative value (Cargill, et al. 1999).
    ++Data sources:  HPI,  COSMIC,  OMIM,  TCGA,  BIOMART,  Greenman2007,  Sjoblom2006,  Ding2008
    *Cross-reference databases: dbSNP
    Interface information was collected from Wang 2012


  • Non-cancer specific variations derived from database dbSNP:


    • No entry in dbSNP was found


  • Cancer-related differential expression proteins derived from database dbDEPC:


    • No entry in dbDEPC was found



    [ continue search ]



    Dr. Jing Li's Group

    ©2015 Menghuan Zhang, Jing Li